The Duke Blue Devils (5-2, 2-1 ACC) and Louisville Cardinals (6-1, 3-1) meet Saturday at Cardinal Stadium. Kickoff is scheduled for 3:30 p.m. ET (ESPN). Below, we analyze BetMGM Sportsbook’s lines around the Duke vs. Louisville odds, and make our expert college football picks and predictions.
The Blue Devils are looking to bounce back after a 38-20 setback at Florida State, and Duke has now lost and failed to cover the spread in 2 of the past 3 games. The defense allowed a season-high point total, too, after having allowed just 59 total points in the 1st 6 games combined.
The big news for Duke is QB Riley Leonard (ankle) is a question mark. The line moved from 4 to 6.5 at some shops due to the injury news, as he aggravated a previous injury in his return at Florida State last weekend.
The Cardinals are looking to rebound after suffering a 38-21 loss at Pittsburgh last time out on Oct. 14. The 38 points allowed by the Cardinals were also a season high, and Louisville had conceded 20 or fewer points in 4 of the previous 5 outings.