Detroit Lions vs Indianapolis Colts Prediction, 8/20/2022 NFL Picks, Best Bets & Odds Preseason Week 2
The Indianapolis Colts (9-8 last year) will compete against the Detroit Lions (3-13-1 last season) at Lucas Oil Stadium on Saturday. Indianapolis opens as 1.5-point dogs. The betting total is set at 40. This games report has current odds, betting predictions, and free picks against the spread.

  
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