The DePaul Blue Demons are set to take on the Creighton Bluejays at CHI Health Center Omaha on Sunday, December 25, 2022. DePaul enters this matchup with a mark of 6-6 for the year. Creighton has a win-loss mark of 6-6 on the year. We have included an expert pick and parlay for todays game against the spread.