Two of the NFL's most storied franchises are set to go toe-to-toe in the Divisional Round of the NFC playoffs, as the San Francisco 49ers host the Dallas Cowboys at Levi's Stadium. Read on for our top NFL picks for the Cowboys-49ers game based on the best NFL odds.
The Cowboys beat the Buccaneers for their first road playoff win since the 1992 NFC Championship (they had lost eight straight), which was just their fourth playoff win in the last 25 seasons. Now Dak Prescott is looking to improve his career playoff record to .500 (he is 2-3 entering this week), while head coach Mike McCarthy is now 11-9 in the playoffs.
San Francisco trailed Seattle at the half but outscored the Seahawks 25-6 in the second half to earn its spot in the Divisional Round. The 49ers finished the season 7-0 against its division and brings an 11-game winning streak into this matchup. In addition, San Francisco's 11 double-digit wins this season are the most of any team.
Here is our best Cowboys vs. 49ers NFL pick for the Divisional Round (odds via FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).