Commanders vs 49ers Prediction: Odds, Picks & Betting Preview Week 16 – December 24, 2022

On Saturday, December 24, 2022, the Washington Commanders (7-6-1) visit a red-hot San Francisco 49ers (10-4) team at Levi’s Stadium. The 49ers are looking to keep on rolling after winning seven games in a row.

49ers vs. Commanders Odds

The spread for this matchup is set at 7 points, with sportsbooks listing the 49ers as the favorites.

As for the moneyline, the 49ers have -320 odds to pick up the win, while the Commanders are listed at +265 to claim victory.

Finally, the over/under for the game is set at 39 points.

  
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