College Football Week 1 Odds, Picks & Prediction: Penn State vs. Purdue (2022)

Let’s take a look at the College Football Week 1 odds, picks, and predictions for this week’s game: Penn State vs. Purdue.

Going 11-11 over his past two seasons, Penn State head coach James Franklin was still awarded a big contract but hasn't quite won over the fan base by most accounts. At the helm, Sean Clifford is back at quarterback for yet another season, as the senior gunslinger has turned into one of the best game managers in the country, but little beyond that.

Freshman running back Nicholas Singleton will get his first shot with the Nittany Lions and could be the spark that this offense needs after scoring just 25 points per game last season.

  
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