College Football Week 1 Early Odds, Picks & Prediction: Middle Tennessee vs. James Madison (2022)

Let’s take a look at the College Football Week 1 odds, picks, and predictions for this week’s game: Middle Tennessee vs. James Madison.

Middle Tennessee +5.5 at James Madison (+180)

After being a force in FCS for years, James Madison is taking the leap to the FBS. They start off hosting Middle Tennessee in Week 1. James Madison has high hopes, but these transitions are rarely seamless. The Dukes lost a lot on both sides of the ball, and life won't be quite as easy as it was for them in the lower division. Middle Tennessee was not great offensively last year but seemed to be putting it together late into the season. The Blue Raiders were able to put up points on some of the weaker opponents on their schedule, and James Madison heads into 2022 fitting that profile. Though the Middle Tennessee defense has holes to fill, they could be negated by James Madison's own offensive holes.

  
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