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The College Football Playoff odds landscape continues to take shape, and a loaded Week 5 of college football action features four ranked vs. ranked matchups. We're diving into all of the action with our college football predictions and best bets for Week 5.
- Indiana and Notre Dame look to bolster their College Football Playoff resumes
- An AP top-25 team's red-hot offense could struggle in a lower-scoring game
- Purdue will have to find ways to get creative offensively when facing Nebraska's stout defensive front
As part of our college football Week 5 predictions, we're hitting you with our four best bets for a loaded weekend of action.
Best college football bets for Week 5
College football odds as of Friday and subject to change. Track the college football scores for the latest line movement and matchup info.
- Devin Mockobee Over 6.5 receiving yards (-115 via bet365) vs. Nebraska ???
- Indiana + Notre Dame moneyline parlay (-102 via FanDuel) ????
- Stanford-Clemson Under 57.5 (-108 via DraftKings) ????
Week 5 college football odds & schedule
(Odds via BetMGM)
- Virginia Tech (+19.5) vs. Miami (-19.5), Friday at 7:30 p.m. ET
- Oklahoma State (+4.5) vs. Kansas State (-4.5), Saturday at noon ET
- Louisville (+6.5) vs. Notre Dame (-6.5), Saturday at 3:30 p.m. ET
- Georgia (-1.5) vs. Alabama (+1.5), Saturday at 7:30 p.m. ET
- Illinois (+17.5) vs. Penn State (-17.5), Saturday at 7:30 p.m. ET
College football player props for Week 5
College football picks made Friday; odds subject to change. Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!
There may not be a better tandem of running backs in the country than Michigan's Kalel Mullings and Donovan Edwards, and their dynamic running ability was a big reason the Wolverines beat then-No. 11 USC despite getting only 32 passing yards from their quarterback.
Mullings and Edwards each have 50-plus carries this season, but Mullings' 8.1 yards per rush is more eye-popping than Edwards' 4.5 and should earn him more looks going forward.
It's obvious whom the Michigan coaching staff trusts more, as Mullings did most of the work with 84 rushing yards on the team's winning 10-play, 89-yard drive in the fourth quarter, including the game-winning touchdown on fourth-and-goal with 37 seconds remaining.
Mullings' O/U is as high as 81.5 at FanDuel, so I am taking advantage of the best price and number at bet365, where a winning $10 wager would pay out $18.70.
Best odds: -115 via bet365 | Implied probability: 53.49%
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Nebraska is coming off a 31-24 overtime loss to Illinois. But prior to that first loss of the season, the Cornhuskers had allowed just 20 points in three games and ranked in the top 20 nationally in both finishing and quality drives.
Nebraska's two biggest strengths defensively are its defensive front, which has recorded 11 sacks thus far, and a secondary that entered last week 42nd in passing success rate. Thus, Purdue is not likely to move the ball consistently on the ground or by throwing to the perimeter.
I expect the Boilermakers to involve their running backs more in the passing game this week, utilizing checkdowns and screen passes to negate Nebraska's pass rush.
Devin Mockobee has just three catches for eight yards this season, but he went Over this projected total in four of nine Big Ten games last year and had five games with catches of 11-plus yards last season.
DraftKings offers +400 odds for Mockobee to record at least 25 receiving yards, but I will instead back the lower total as a safer wager.
Best odds: -115 via bet365 | Implied probability: 53.49%
College football game predictions for Week 5
This is pure coincidence that the two teams we identified for our moneyline parlay hail from the same state, but neither looks vulnerable as a home favorite.
Notre Dame typically doesn't end the first month of a season with multiple losses, as it has won nine of its last 10 games (and covered at a 70% clip) while playing with one loss in September.
Louisville didn't go up double-digits on Georgia Tech until midway through the fourth quarter last week, and with this being the Cardinals' first road game of the season, I would want to see them be a little more battle-tested before backing them with confidence to win a game of this magnitude.
Meanwhile, Curt Cignetti is one of the best college football coaches in the country that casual bettors may not have heard of, as he has seamlessly instilled the culture that made James Madison instantly successful at the FBS level in his new tenure as Hoosiers head coach.
Indiana's offense ranks second in success rate and fifth in EPA. It should have too much for a Maryland offense that was limited to just 2.8 yards per carry in its only Big Ten game this year against Michigan State.
Based on FanDuel's cheap -250 moneyline odds to back Indiana (the Hoosiers are -278 favorites at Caesars), it offers the best odds for this parlay. By combining Indiana and Notre Dame to win outright, I am getting two teams at -250 or higher at multiple shops for -102 odds, where a winning $10 wager would net $9.80 in profits.
Best odds: -102 via FanDuel | Implied probability: 50.50%
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It seems like light years ago that Clemson was held to three points and 188 total yards in a Week 1 loss to Georgia, given how dominant its offense has been since.
In Weeks 2 and 3, the Tigers have averaged 62.5 points, 617.5 yards, 269.0 rushing yards, while allowing 27.5 points per game. Clemson has a plus-70 point differential in the last two games, and its 125 points in that span are the second-most in a two-game span since 1936.
All of that, coupled with Clemson's 59-35 win over NC State last week make this total feel inflated.
The Tigers had a 52-7 lead midway through the third quarter and allowed their next four touchdowns in garbage time when several starters were already pulled. Meanwhile, Stanford does not project to light up the scoreboard this week with quarterback Ashton Daniels, who has a 4-3 TD-INT ratio and has completed fewer than 62% of his passes this season.
All of our best sports betting sites are in unison with a total of 57.5 points for this contest, but DraftKings is the only one charging less than the standard -110 juice to back the Under. A $10 winning wager would pay out $19.09.
Best odds: -108 via DraftKings | Implied probability: 51.92%
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