College football odds, lines, spreads: Picks, predictions, betting advice for Week 5, 2022 from proven model
College football odds, lines, spreads: Picks, predictions, betting advice for Week 5, 2022 from proven model

There are five matchups of AP Top 25 teams during the Week 5 schedule, and the action gets started early with No. 7 Kentucky traveling to No. 14 Ole Miss. The Week 5 college football odds from Caesars Sportsbook list the Rebels as 6.5-point favorites in that one. Elsewhere in the SEC, No. 2 Alabama travels to No. 20 Arkansas (+15.5) in the 3:30 p.m. ET SEC on CBS matchup. In the ACC, it's No. 22 Wake Forest vs. No. 23 FSU (-6) and No. 10 NC State vs. No. 5 Clemson (-6.5). And Big 12 contenders square off as No. 9 Oklahoma State goes to No. 16 Baylor (-2.5).'

Before making any college football picks for those games or others in Week 5, be sure to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It entered Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen HUGE returns!

Now, it has studied the latest college football odds from Caesars (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for Week 5 of FBS college football, and the results are in.'

  
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