The Week 4 college football schedule is loaded with ranked vs. ranked matchups, including No. 9 Notre Dame vs. No. 6 Ohio State. Notre Dame stayed unbeaten with its 41-17 win over Central Michigan last week, while Ohio State cruised to a 63-10 win against Western Kentucky. The Buckeyes are 3-point road favorites in the Week 4 college football odds from SportsLine consensus. Another enticing matchup on Saturday night features No. 7 Penn State (-14) vs. No. 24 Iowa in a Big Ten on CBS showdown.'
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