College Football Expert Picks Week 5: Top CFB Predictions This Week
College Football Expert Picks Week 5: Top CFB Predictions This Weekiv class=”bodyContent col-lg-9 mb-3″>

The best slate of games to date this college football season takes place this weekend as we make our Week 5 college football expert picks.

  • After tumbling down the College Football Playoff odds, USC has a chance to get back on track against Wisconsin
  • Texas is set to begin SEC play with Arch Manning likely to make his second start as he tries to climb the Heisman Trophy odds
  • Georgia heads to Alabama as a 1.5-point favorite in a matchup of college football championship odds favorites in Tuscaloosa

As part of our Week 5 college football predictions, our experts are making their best bets on the can't-miss games this week.

College football expert picks for Week 5

College football odds as of Thursday and subject to change. See all of our college football picks for more on this week's top matchups.

Rob Paul C Jackson Cowart
Wisconsin vs. USC Woody Marks Over 79.5 rushing yards (-114 via FanDuel) USC Over 32.5 points (-115 via FanDuel)
Mississippi State vs. Texas Jaydon Blue 2+ touchdowns (+120 via bet365) Texas Over 49.5 points (+102 via FanDuel)
Georgia vs. Alabama Ryan Williams Over 46.5 receiving yards (-119 via Caesars)  Alabama +2 (-110 via bet365)
Illinois vs. Penn State Nicholas Singleton Over 79.5 rushing yards (-115 via Caesars) Illinois +18 (-108 via DraftKings)
Arizona vs. Utah Micah Bernard Over 98.5 rushing yards (-115 via bet365) Arizona +8.5 (-112 via DraftKings)
Oregon vs. UCLA Dillon Gabriel Over 2.5 passing TDs (+106 via FanDuel) Over 55 (-108 via DraftKings)

Top picks for Week 5

Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Marks has hit 100-plus rushing yards in back-to-back games, including against a Michigan defense that's fifth in SP+. He has USC's offense sitting 10th in EPA per rush.

Meanwhile, Wisconsin allows the fourth-most rushing yards in the Big Ten (141.3) and is 113th in EPA per rush on defense. If Marks hits the Over, a $10 bet pays an $8.77 profit. 

Best odds: -114 via FanDuel | Implied probability: 53.27%

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