Cleveland Guardians at Cincinnati Reds odds, picks and predictions

The Cleveland Guardians (57-62) and the Cincinnati Reds (62-58) open a 2-game interleague series at Great American Ball Park Tuesday. First pitch is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; teams split 2-2 in 2022

The Guardians won 9-2 Sunday at Tropicana Field, salvaging the final contest in a 3-game set against the Tampa Bay Rays. After a 5-0 Under run, the Over cashed in all 3 outings against the Rays. Cleveland has scored 4 or more runs in 4 straight contests for the 1st time since July 17-21.

The Reds took 2 of 3 games from the Pittsburgh Pirates over the weekend, including a split of a doubleheader Sunday after rains washed away Saturday’s contest. The Over cashed in 2 of the 3 games, but the Under is still 8-2 in the last 10 games.

  
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