Clemson vs. Notre Dame Football Prediction, Odds & Best Bets

To the surprise of some, Clemson ended up in the top four of this week's College Football Playoff rankings ahead of Michigan. But will it be a short stay for the Tigers? A big test could be ahead at Notre Dame on Saturday night.

This will be the Tigers' first game since they needed to rally to defeat Syracuse 27-21 at home two weeks ago.

They were down 21-10 to the Orange in the third quarter when starting QB DJ Uiagalelei was pulled in favor of freshman Cade Klubnik, and the switch paid off with 17 unanswered points to finish the game.

Uiagalelei is still the starter ahead of the non-conference matchup with the Fighting Irish, who are coming off of a 41-24 win at Syracuse last weekend.

  
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