The Kansas City Chiefs (0-0) visit State Farm Stadium to take on the Arizona Cardinals (0-0) on Sep. 11. Kickoff is scheduled for 4:25pm ET in Glendale.
The Chiefs are betting favorites in Week 1, with the spread sitting at -3.5 (-110).
The Chiefs vs. Cardinals Over/Under is 53.5 total points for the game.
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Chiefs vs. Cardinals Prediction for Week 1
Based on recent trends the model predicts the Cardinals will win this Week 1 NFL matchup with 68.0% confidence.
This prediction factors in up-to-date player injuries for both the Chiefs and Cardinals, plus offensive & defensive matchups, recent games and key player performances this season.
Best Chiefs Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for Chiefs players for Week 1, looking at profitable historical betting trends:
- Patrick Mahomes has hit the Passing Yards Under in 13 of his last 18 games (+6.90 Units / 31% ROI)
- Patrick Mahomes has hit the Rushing Yards Over in 6 of his last 7 away games (+5.00 Units / 62% ROI)
- Mecole Hardman has hit the Receptions Under in 6 of his last 7 games (+4.35 Units / 38% ROI)
- Patrick Mahomes has hit the Completions Over in his last 4 away games (+4.20 Units / 97% ROI)
- Clyde Edwards-Helaire has hit the Receiving Yards Under in 7 of his last 10 games (+3.30 Units / 27% ROI)
Best Cardinals Player Prop Best Bets Today
And here are some top NFL player prop bets for Cardinals players for Week 1, looking at profitable historical betting trends:
- Zach Ertz has hit the Receiving Yards Over in his last 6 games at home (+6.00 Units / 86% ROI)
- DeAndre Hopkins has hit the Receptions Under in 8 of his last 10 games (+5.85 Units / 41% ROI)
- DeAndre Hopkins has hit the Receiving Yards Under in 8 of his last 10 games (+5.50 Units / 44% ROI)
- Rondale Moore has hit the Receiving Yards Under in 9 of his last 12 games (+5.15 Units / 33% ROI)
- James Conner has hit the Carries Under in his last 5 games at home (+5.00 Units / 79% ROI)
Chiefs Betting Trends: ATS, Moneyline, Over/Under
- The Kansas City Chiefs have hit the 1Q Moneyline in 10 of their last 13 games (+10.00 Units / 38% ROI)
- The Kansas City Chiefs have scored first in 13 of their last 16 games (+8.20 Units / 30% ROI)
- The Kansas City Chiefs have covered the 1Q Spread in 10 of their last 13 games (+7.10 Units / 50% ROI)
- The Kansas City Chiefs have hit the Game Total Over in 7 of their last 8 games (+5.90 Units / 67% ROI)
- The Kansas City Chiefs have hit the Moneyline in 11 of their last 13 games (+5.80 Units / 13% ROI)
Cardinals Betting Trends: ATS, Moneyline, Over/Under
- The Arizona Cardinals have hit the 4Q Game Total Under in 13 of their last 18 games (+7.70 Units / 39% ROI)
- The Arizona Cardinals have hit the 3Q Game Total Over in 8 of their last 11 games (+5.90 Units / 48% ROI)
- The Arizona Cardinals have hit the 2H Game Total Over in 8 of their last 11 games (+5.70 Units / 47% ROI)
- The Arizona Cardinals have hit the 2Q Game Total Under in 7 of their last 11 games (+3.75 Units / 31% ROI)
- The Arizona Cardinals have hit the 4Q Moneyline in 4 of their last 7 games at home (+1.35 Units / 12% ROI)
Kansas City Chiefs: Keys to the Game vs. the Arizona Cardinals
The Chiefs were 1-2 (.333) when rushing less than 20 times last season — tied for 3rd-best in NFL; League Avg: .121.
The Chiefs were 2-2 (.500) when the opposing team rushes more than 30 times last season — tied for best in NFL; League Avg: .165.
The Chiefs were undefeated (8-0) when allowing less than 22 points last season — tied for best in NFL; League Avg: .762.
The Chiefs were 8-4 (.667) when sacking the QB less than 3 times last season — tied for 2nd-best in NFL; League Avg: .407.
Arizona Cardinals: Keys to the Game vs. the Kansas City Chiefs
The Cardinals were 8-3 (.727) when allowing less than 3 sacks last season — seventh-best in NFL. The Chiefs averaged just 1.8 sacks per game over that time span — tied for third-worst in NFL.
The Cardinals were winless (0-4) when the opposing team rushes more than 30 times last season — tied for worst in NFL; League Avg: .165.