Chicago White Sox at Detroit Tigers odds, picks and predictions

The Chicago White Sox (21-31) and Detroit Tigers (23-25) meet Friday for the 2nd game of a 4-game series at Comerica Park. First pitch is slated for 6:40 p.m. ET (Apple TV+). Let’s analyze FanDuel Sportsbook’s lines around the White Sox vs. Tigers odds and make our expert MLB picks and predictions for the best bets.

Season series: Detroit leads 1-0

Chicago mustered just 4 hits in a 7-2 series-opening loss Thursday. The White Sox entered the series with a .542 OPS over their last 7 road games.

Detroit took 2 of 3 contests from the Kansas City Royals in a Monday-Wednesday set in K.C., so the Bengals are now 3-1 over their last 4 games. That comes on the heels of a 3-5 spell from May 12-21 where Detroit logged a .594 OPS.

White Sox at Tigers projected starters

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