The Chicago White Sox (61-58) and Cleveland Guardians (63-55) open a 3-game set at Progressive Field. Friday’s series opener is slated for a 7:05 p.m. ET first pitch. Let’s analyze Tipico Sportsbook’s lines around the White Sox vs. Guardians odds with MLB picks and predictions.
Season series: Cleveland leads 8-5
The White Sox have lost 2 straight after winning 5 in a row from Aug. 12-16. Chicago had a fine 2nd-half ERA of 3.39 until coughing up 21 runs in Thursday’s loss to the Houston Astros.
The Guardians have pitched themselves to a 12-6 record since July 31. Cleveland owns a 3.24 ERA, 1.09 WHIP over that productive stretch.