The Chicago Cubs (57-60) and Chicago White Sox (28-89) begin a 2-game series Friday. First pitch from Guaranteed Rate Field is set for 8:10 p.m. ET. Let's analyze FanDuel Sportsbook's lines around the'Cubs vs. White Sox odds'and make our expert'MLB picks and predictions'for the best bets.
Season series: Cubs lead 2-0 with a pair of 7-6 wins June 4-5
The Cubs finished their homestand 5-2 with a 8-2 victory over the Minnesota Twins on Wednesday. They outscored opponents 36-22 in the 7 games at Wrigley. The Cubs are 25-33 on the road and 55-62 against the spread (ATS).
The White Sox limp home to face their crosstown rivals after snapping a 21-game losing streak on Tuesday, before losing 3-2 on Wednesday to the Oakland Athletics and firing manager Pedro Grifol. The White Sox were outscored 38-19 in losing 5 of 6 on the road trip. The Southsiders are 17-40 at home and 50-66 ATS.