The Los Angeles Chargers (8-6) visit Lucas Oil Stadium to take on the Indianapolis Colts (4-9) on Dec. 26. Kickoff is scheduled for 8:15pm EST in Indianapolis for Monday Night Football.
The Chargers are betting favorites in Week 16, with the spread sitting at -4 (-110).
The Chargers vs. Colts Over/Under is 47 total points for the game.
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Chargers vs. Colts Prediction for Week 16
Based on recent trends, the winning team model predicts the Chargers will win this Week 16 game with 69.3% confidence.
Based on recent against-the-spread trends, the model predicts the Chargers will cover the spread this Week 16 with 62.0% confidence.
Both predictions factor in up-to-date player injuries for both the Chargers and Colts, plus offensive & defensive matchups, recent games and key player performances this season.
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Best Chargers Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for Chargers players for Week 16, looking at profitable historical betting trends:
- Justin Herbert has hit the Completions Over in 12 of his last 16 games (+7.70 Units / 44% ROI)
- Gerald Everett has hit the Receptions Over in 11 of his last 15 games (+6.80 Units / 40% ROI)
- Austin Ekeler has hit the Receiving Yards Over in 11 of his last 16 games (+5.35 Units / 29% ROI)
- Justin Herbert has hit the Pass Attempts Over in 11 of his last 16 games (+5.25 Units / 29% ROI)
- Austin Ekeler has hit the Receptions Over in 10 of his last 15 games (+5.20 Units / 29% ROI)
Best Colts Player Prop Best Bets Today
And here are some top NFL player prop bets for Colts players for Week 16, looking at profitable historical betting trends:
- Michael Pittman has hit the Receptions Over in 12 of his last 16 games (+7.95 Units / 43% ROI)
- Jonathan Taylor has hit the Rushing Yards Under in his last 6 games at home (+6.00 Units / 76% ROI)
- Parris Campbell has hit the Receiving Yards Over in 8 of his last 11 games (+4.75 Units / 39% ROI)
- Alec Pierce has hit the Receptions Under in 7 of his last 9 games (+4.60 Units / 33% ROI)
- Jonathan Taylor has hit the Receiving Yards Under in 5 of his last 6 games at home (+3.80 Units / 50% ROI)
Chargers Best Bets for Week 16:
- The Los Angeles Chargers have covered the 2Q Spread in 13 of their last 16 games (+9.35 Units / 52% ROI)
- The Los Angeles Chargers have hit the 2H Game Total Under in 9 of their last 10 games (+9.05 Units / 83% ROI)
- The Los Angeles Chargers have hit the 2Q Moneyline in 12 of their last 16 games (+8.75 Units / 39% ROI)
- The Los Angeles Chargers have hit the Team Total Under in 11 of their last 14 games (+7.90 Units / 50% ROI)
- The Los Angeles Chargers have hit the 2Q Game Total Over in 9 of their last 12 games (+6.65 Units / 47% ROI)
Colts Best Bets for Week 16:
- The Indianapolis Colts have hit the Team Total Under in 13 of their last 17 games (+8.30 Units / 43% ROI)
- The Indianapolis Colts have hit the 1H Game Total Under in 12 of their last 17 games (+7.55 Units / 40% ROI)
- The Indianapolis Colts have hit the 1Q Game Total Under in 12 of their last 16 games (+7.25 Units / 37% ROI)
- The Indianapolis Colts have hit the Game Total Under in 12 of their last 17 games (+6.50 Units / 35% ROI)
- The Indianapolis Colts have covered the 3Q Spread in 9 of their last 12 games (+6.05 Units / 41% ROI)
Chargers Against the Spread (ATS) Record
Against the spread this NFL season, the Chargers have gone 8-5 (+2.5 Units / 16.39% ROI).
- Chargers are 8-6 when betting on the Moneyline for -0.45 Units / -2.07% ROI
- Chargers are 5-8 when betting the Over for -3.8 Units / -24.68% ROI
- Chargers are 8-5 when betting the Under for +2.5 Units / ROI
Colts Against the Spread (ATS) Record
Against the spread this NFL season, the Colts have gone 6-8 (-2.65 Units / -17.49% ROI).
- Colts are 4-9 when betting on the Moneyline for -5.35 Units / -27.94% ROI
- Colts are 5-9 when betting the Over for -4.9 Units / -31.82% ROI
- Colts are 9-5 when betting the Under for +3.5 Units / 22.73% ROI
Los Angeles Chargers: Keys to the Game vs. the Indianapolis Colts
The Chargers are 5-1 (.833) when allowing less than 3 explosive runs this season — 5th-best in NFL; League Avg: .568.
The Chargers are undefeated (5-0) when allowing less than 22 points this season — tied for best in NFL; League Avg: .712.
The Chargers are 7-2 (.778) when favorites this season — tied for 8th-best in NFL; League Avg: .643.
The Chargers are 5-3 (.625) when within 7 points entering the 4th quarter this season — tied for 9th-best in NFL; League Avg: .496.
Indianapolis Colts: Keys to the Game vs. the Los Angeles Chargers
The Colts are 1-4-1 (.167) when favorites this season — 3rd-worst in NFL; League Avg: .643.