Chargers vs. 49ers Computer Picks, NFL Odds and Prediction for Sunday Night Football on November 13, 2022

The Los Angeles Chargers take on the San Francisco 49ers in what should be a very entertaining Sunday Night Football matchup at 8:20PM ET on November 13. Los Angeles comes into this game after having won four of its last five, but San Francisco is coming off a big win over the LA Rams last week. And Kyle Shanahan's group should only continue to get stronger as Christian McCaffrey gets more and more comfortable in the offense.  

Find out how we think this one will play out in our Chargers vs. 49ers betting preview.

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Chargers vs. 49ers Computer Picks

  • No edge on either team to cover the 7-point spread
  • 74% chance the 49ers win on the moneyline
  • 51% probability on Chargers vs. 49ers going Over 45

For the best NFL computer picks, check out our Chargers vs. 49ers data predictions. They are constantly updating based on hundreds of different data points.

 

Chargers vs. 49ers Odds and Betting Lines

  
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By Dimers