Cardinals vs Rams Prediction, Odds & Best Prop Bets: NFL, Week 6
Cardinals vs Rams Prediction, Odds & Best Prop Bets: NFL, Week 6

The Arizona Cardinals (1-4) visit SoFi Stadium to take on the Los Angeles Rams (2-3) on Oct. 15. Kickoff is scheduled for 4:25pm EDT in Inglewood.

The Rams are betting favorites in this Week 6 matchup, with the spread sitting at -6.5 (-110).

The Cardinals vs. Rams Over/Under is 48.5 total points for the game.

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Cardinals vs. Rams Prediction

Based on recent trends, the winning team model predicts the Rams will win this Week 6 game with 71.0% confidence.

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread with 53.0% confidence.

Both predictions factor in up-to-date player injuries for both the Cardinals and Rams, plus offensive & defensive matchups, recent games and key player performances this season.


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Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for Cardinals players this Week 6 game, looking at profitable historical betting trends:

  • James Conner has hit the Longest Rush Over in his last 7 games (+7.00 Units / 85% ROI)
  • James Conner has hit the Rushing Yards Over in 9 of his last 11 games (+6.60 Units / 52% ROI)
  • Kyler Murray has hit the Passing Yards Under in 7 of his last 8 games (+5.80 Units / 55% ROI)
  • James Conner has hit the Carries Under in 8 of his last 10 games (+5.30 Units / 40% ROI)
  • Zach Ertz has hit the Longest Reception Under in 8 of his last 10 games (+5.10 Units / 38% ROI)

Best Rams Player Prop Best Bets Today

And here are some top NFL player prop bets for Rams players for this matchup, looking at profitable historical betting trends:

  • Matthew Stafford has hit the Passing Yards Under in 8 of his last 10 games (+5.50 Units / 45% ROI)
  • Ben Skowronek has hit the Receiving Yards Over in 5 of his last 6 games at home (+3.90 Units / 57% ROI)
  • Cooper Kupp has hit the Longest Reception Under in 7 of his last 10 games (+3.30 Units / 27% ROI)
  • Matthew Stafford has hit the TD Passes Under in 4 of his last 5 games at home (+3.15 Units / 57% ROI)
  • Matthew Stafford has hit the Completions Over in 4 of his last 5 games at home (+3.15 Units / 54% ROI)

  • The Arizona Cardinals have hit the 2Q Game Total Over in 12 of their last 17 games (+7.40 Units / 38% ROI)
  • The Arizona Cardinals have hit the 1H Game Total Over in 13 of their last 20 games (+7.35 Units / 34% ROI)
  • The Arizona Cardinals have hit the Team Total Over in 13 of their last 20 games (+5.25 Units / 23% ROI)
  • The Arizona Cardinals have covered the 2Q Spread in 11 of their last 17 games (+4.95 Units / 26% ROI)
  • The Arizona Cardinals have hit the Game Total Over in 12 of their last 20 games (+4.30 Units / 20% ROI)

  • The Los Angeles Rams have hit the 3Q Game Total Under in 7 of their last 8 games at home (+5.90 Units / 61% ROI)
  • The Los Angeles Rams have hit the 1H Game Total Over in 8 of their last 10 games at home (+5.90 Units / 55% ROI)
  • The Los Angeles Rams have hit the 2Q Game Total Over in 6 of their last 8 games at home (+3.85 Units / 43% ROI)
  • The Los Angeles Rams have hit the 4Q Game Total Over in 6 of their last 8 games at home (+3.80 Units / 42% ROI)
  • The Los Angeles Rams have hit the Game Total Over in 7 of their last 10 games at home (+3.70 Units / 34% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals went 3-2 (+0.9 Units / 16.67% ROI).

  • Cardinals are 1-4 when betting on the Moneyline for +0.75 Units / 15% ROI
  • Cardinals are 4-1 when betting the Over for +2.9 Units / 52.73% ROI
  • Cardinals are 1-4 when betting the Under for -3.4 Units / ROI

Rams Against the Spread (ATS) Record

Against the spread this NFL season, the Rams went 2-1 (+0.9 Units / 16.67% ROI).

  • Rams are 2-3 when betting on the Moneyline for -0.2 Units / -3.81% ROI
  • Rams are 2-3 when betting the Over for -1.3 Units / -23.64% ROI
  • Rams are 3-2 when betting the Under for +0.8 Units / 14.55% ROI

Arizona Cardinals: Keys to the Game vs. the Los Angeles Rams

The Cardinals were winless (0-4) when within 7 points at the two minute warning in the 2022 season — worst in NFL; League Avg: .492.

The Cardinals are 1-8 (.111) when sacking the QB 3 or more times since the 2022 season — worst in NFL; League Avg: .626.

The Cardinals are winless (0-6) when within 7 points at the two minute warning since the 2022 season — worst in NFL; League Avg: .494.

The Cardinals are winless (0-4) when within 3 points at the two minute warning since the 2022 season — tied for worst in NFL; League Avg: .494.

Los Angeles Rams: Keys to the Game vs. the Arizona Cardinals

The Rams are 2-13 (.133) when making less than 5 explosive passes in a game since the 2021 season — worst in NFL; League Avg: .431.

The Rams are winless (0-11) when making less than 5 explosive passes in a game since the 2022 season — worst in NFL; League Avg: .438.

The Rams are 3-15 (.167) when making less than 7 explosive plays since the 2021 season — 2nd-worst in NFL; League Avg: .394.

The Rams are 2-12 (.143) when making less than 7 explosive plays since the 2022 season — tied for 2nd-worst in NFL; League Avg: .382.

Additional Matchup Notes for Arizona Cardinals vs. Los Angeles Rams

  
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