Shortly after the Denver Broncos covered the spread in a Week 14 loss to the Kansas City Chiefs – for their first ATS winning streak since mid-2021 – they opened as a 2.5-point home underdog in NFL odds against the Arizona Cardinals in Week 15.
Two days later, the Broncos flipped to a 2.5-point favorite after Kyler Murray suffered a season-ending injury in the Cardinals' loss to the New England Patriots on Monday Night Football.
Same spread, different favorite for Sunday afternoon in Denver.
How Common Is a 2.5-Point Spread?
Since 2003, approximately 7.3% of all regular-season spreads closed at 2.5. It's the fourth-most common number, behind only 3 (17.6%), 3.5 (10.8%), and 1 (10.2%).