What better way to kick off the 2022 NFL season than with the defending champions hosting the Super Bowl favorites? That’s what we have Thursday night with the Los Angeles Rams taking on the Buffalo Bills at SoFi Stadium. Kickoff is set for 8:20 p.m. ET (NBC) from Inglewood. Below, we analyze Tipico Sportsbook’s lines around the Bills vs. Rams odds, and make our expert NFL picks and predictions.
The Rams are the reigning Super Bowl champions after beating the Cincinnati Bengals in February in their home stadium. They’re among the betting favorites in the NFC, close behind the Tampa Bay Buccaneers and Green Bay Packers. Though they suffered some key losses in the offseason, including OLB Von Miller and RG Austin Corbett, the Rams are built to contend for another championship this season.
The Bills are the betting favorites to win it all this season after coming close to reaching the big game last year. Led by QB Josh Allen, the Bills added Miller in free agency and return star players such as CB Tre’Davious White and WR Stefon Diggs. They boasted the No. 1 defense in football last season, but that very defense was unable to stop the Chiefs in the AFC divisional round last postseason.
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