Buffalo Bills at Carolina Panthers odds, picks and prediction
Buffalo Bills at Carolina Panthers odds, picks and prediction

The Buffalo Bills (2-0) and Carolina Panthers (1-1) wrap up their preseason schedule Friday. Kickoff from Bank of America Stadium is scheduled for 7 p.m. ET. Below, we analyze Tipico Sportsbook’s lines around the Bills vs. Panthers odds, and make our best NFL picks, predictions and bets.

The Bills throttled the visiting Denver Broncos 42-15 last weekend, playing the starters for most of the 1st quarter. But the run game continued to be impressive well after the 1st unit was out of there, showing some tremendous organizational depth.

Coach Sean McDermott confirmed early this week that most of his 1st-team players will not play Friday in Charlotte, including star QB Josh Allen.

The Panthers were on the short end of a 20-10 loss at New England after joint practices with the Patriots last week. The only touchdown came via pick-6 from DB Tae Hayes, too.

  
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