The Buffalo Bills look to extend a run of preseason dominance with a visit to the Carolina Panthers Friday. We break down the Bills-Panthers matchup with our top NFL preseason picks.
Despite winning each of their last 10 preseason games, the Bills are 6-point underdogs when they conclude their 2022 exhibition campaign Friday against the Panthers.
The Panthers split their first two preseason contests and are expected to play a lot of starters in Week 3, while QB Josh Allen and other Bills regulars aren't likely to see action.
We break down the matchup in our Bills-Panthers NFL football picks for preseason Week 3 (odds via DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).