Bills vs. Lions Prediction: Week 12 Odds, Picks & Moneyline – November 24, 2022

The Detroit Lions (4-6) are putting their three-game winning streak to the test when they square off against the Buffalo Bills (7-3) at Ford Field on Thursday, November 24, 2022.

Bills vs. Lions Odds

The spread for this matchup is set at 9 points, with oddsmakers listing the Bills as the favorites.

As for the moneyline, the Bills have -410 odds to pick up the win, while the Lions are listed at +330 to claim victory.

Finally, the total for the game is set at 53.5 points.

  
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