Two AFC teams play their second preseason game when the Buffalo Bills host the Denver Broncos on Saturday at Highmark Stadium in Buffalo. Both teams enter the game 1-0 in the preseason. Last week the Bills rallied to beat the Colts, 27-24, despite sitting out almost all of its starters on both sides of the ball. Meanwhile the Broncos did not play new quarterback Russell Wilson but still defeated a sloppy Cowboys team, 17-7.'
Kickoff is set for 1 p.m. ET. Buffalo is a 6-point favorite in the latest Bills vs. Broncos odds from Cae sars Sportsbook, while the over/under for total points scored is 42.
Before you make any Broncos vs. Bills picks or NFL preseason predictions, you NEED to see which side SportsLine analyst and Denver expert Matt Severance is on.'
Severance is a well-connected writer and handicapper who has worked in the industry since 2005. He enters the 2022 NFL season on a roll. He is 22-10 (+1076) in his last 32 NFL picks against-the-spread. He also has a keen eye for the Broncos, going 9-2 (+670) in his last 11 picks in games involving Denver.