Best NCAA Tournament Sweet 16 upset picks and predictions

The best weekend of the year is over, and now we enter the weekend with the Sweet 16 and Elite Eight. Below, we break down Tipico Sportsbook’s NCAA Tournament odds and lines and list the best Sweet 16 upset bets'to cash in on among SportbookWire’s expert college basketball picks and predictions.

There are 4 teams that sit outside of the top-6 seeds, No. 9 FAU, No. 15 Princeton, No. 7 Michigan State, and No. 8 Arkansas.

With No. 1 seeds like Kansas and Purdue having already fallen, fans will have all eyes on Houston and Alabama to make sure they don’t go down as well. As with every week of March Madness, expect chaos to ensue.

Check out: USA TODAY Sports Coaches Poll

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NCAA Tournament Sweet 16 upset picks

  
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