OddsJam's MLB experts take you through the betting odds, picks and predictions for this MLB matchup between the Houston Astros vs. the Tampa Bay Rays on September 21, 2022 in Tampa Bay.
Opening Lines via DraftKings Sportsbook
As a note, all odds in this preview of Astros vs. Rays are from opening lines. Odds can move at any time. Please check the table below for real-time betting odds!
The Houston Astros visit the Tampa Bay Rays for this MLB matchup on September 21, 2022. First pitch for Wednesday's game is 6:40 p.m. ET / 3:40 p.m. PT in Tampa Bay.
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