Arizona Cardinals at San Francisco 49ers odds, picks and predictions
Arizona Cardinals at San Francisco 49ers odds, picks and predictions

The Arizona Cardinals (4-12) wrap up their season on the road in Week 18 against the NFC West champion San Francisco 49ers (12-4). Sunday’s kickoff at Levis Stadium is at 4:25 p.m. ET (FOX). Below, we analyze Tipico Sportsbook’s'lines around the Cardinals vs. 49ers odds, and make our expert NFL picks and predictions.

The Cardinals have lost 6 straight games and 8 of their last 9. They lost 20-19 last week to the Atlanta Falcons on the final play of the game, but did cover' the 7-point spread as road underdogs. After starting 4 different QBs in 4 games, David Blough'will make his 2nd consecutive start.

The 49ers head to the postseason with a shot at the No. 1 seed in the NFC. They have won 9 consecutive games and the last 4 with 7th-round rookie QB Brock Purdy'starting in place of the injured'Jimmy Garoppolo. They picked up a 37-34 overtime win over the Las Vegas Raiders last week, but failed to cover the 10-point spread as road favorites.

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Cardinals at 49ers odds

  
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