The Louisville Cardinals (6-3) visit Memorial Stadium to take on the Clemson Tigers (8-1) on Nov. 12. Kickoff is scheduled for 3:30pm EST in Clemson.
Clemson are betting favorites in Week 11, with the spread sitting at -7 (-110).
The Over/Under for Louisville vs. Clemson is 51.5 total points.
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Louisville vs Clemson Prediction for Week 11
Based on recent trends, the winning team model predicts Clemson will win this game with 63.6% confidence.
Louisville vs Clemson Spread Prediction for Week 11
Based on recent against-the-spread trends, the model predicts Louisville will cover the spread with 58.1% confidence.
Both predictions factor in up-to-date player injuries for both Louisville and Clemson, plus offensive & defensive matchups, recent games and key player performances this season.
Best Louisville Player Prop Bets Today
We’ve highlighted some favorite college football player prop bets for Louisville players for Week 11, looking at profitable historical betting trends:
- Malik Cunningham has hit the TD Passes Under in 10 of his last 11 games (+7.75 Units / 46% ROI)
- Malik Cunningham has hit the Passing Yards Under in 6 of his last 7 games (+4.65 Units / 55% ROI)
Best Clemson Player Prop Best Bets Today
Top NCAAF player prop bets for Clemson players for Week 11, looking at profitable historical betting trends:
- DJ Uiagalelei has hit the Passing Yards Under in 10 of his last 13 games (+6.40 Units / 41% ROI)
- Joseph Ngata has hit the Receiving Yards Under in 6 of his last 7 games (+4.80 Units / 57% ROI)
- DJ Uiagalelei has hit the TD Passes Under in 6 of his last 9 games (+3.10 Units / 25% ROI)
- DJ Uiagalelei has hit the Rushing Yards Under in his last 3 games (+3.00 Units / 82% ROI)
Louisville Best Bets & Trends for ATS, Moneyline & Totals
- Louisville has hit the 1Q Game Total Over in 12 of their last 19 games (+7.50 Units / 35% ROI)
- Louisville has hit the 1H Game Total Under in 7 of their last 9 games (+4.75 Units / 47% ROI)
- Louisville has hit the Team Total Over in 9 of their last 13 games (+4.45 Units / 30% ROI)
- Louisville has hit the Moneyline in their last 4 games (+4.30 Units / 75% ROI)
- Louisville have covered the Spread in their last 4 games (+4.00 Units / 91% ROI)
Clemson Best Bets & Trends for ATS, Moneyline & Totals
- Clemson has hit the Moneyline in 13 of their last 15 games (+10.20 Units / 13% ROI)
- Clemson has hit the 1H Game Total Under in 13 of their last 20 games (+5.35 Units / 24% ROI)
- Clemson has hit the 1H Moneyline in 12 of their last 17 games (+5.00 Units / 6% ROI)
- Clemson has hit the 1Q Moneyline in 6 of their last 11 games (+4.40 Units / 12% ROI)
- Clemson has hit the 1Q Game Total Under in 12 of their last 20 games (+3.95 Units / 17% ROI)
Louisville Against the Spread (ATS) Record
Louisville has gone 6-3 against the spread this college football season (+2.75 Units / 27.92% ROI).
- Louisville is 6-3 when betting on the Moneyline for -0.85 Units / -4.19% ROI
- Louisville is 4-5 when betting the Over for -1.5 Units / -15.15% ROI
- Louisville is 5-4 when betting the Under for +0.6 Units / 6.06% ROI
Clemson Against the Spread (ATS) Record
Clemson has gone 4-4 against the spread this college football season (-0.4 Units / -4.52% ROI).
- Clemson is 6-1 when betting on the Moneyline for +4.2 Units / 8.2% ROI
- Clemson is 4-4 when betting the Over for -0.4 Units / -4.55% ROI
- Clemson is 4-4 when betting the Under for -0.4 Units / -4.55% ROI
Louisville is 2-12 (.143) when allowing 5 or more explosive passes since the 2020 season– 3rd-worst among Power 5 Teams; Average: .450
Louisville is 2-15 (.118) when allowing 22 or more points since the 2020 season– tied for 7th-worst among Power 5 Teams; Average: .302
Louisville is 3-12 (.167) when converting less than 50% of third down conversion opportunities since the 2020 season– tied for 7th-worst among Power 5 Teams; Average: .361
Louisville is 4-13 (.235) when allowing 200 or more passing yards since the 2020 season– 6th-worst among Power 5 Teams; Average: .465
#5 Clemson is undefeated (8-0) when not throwing an interception — tied for best in FBS; Average: .578
#5 Clemson is undefeated (9-0) when averaging more than 5 yards on first down plays — 2nd-best among Power 5 Teams; Average: .424