The Kansas City Chiefs and San Francisco 49ers face off in a game filled with playoff implications at 4:25PM ET on Sunday, October 23.
Find out how we think this one will play out in our Chiefs vs. 49ers betting preview.
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Chiefs vs. 49ers Computer Picks
- 56% chance the Chiefs cover the -3 spread
- 63% chance the Chiefs win on the moneyline
- 51% chance the Over/Under 48 points goes over