The Jacksonville Jaguars (2-3) visit Lucas Oil Stadium to take on the Indianapolis Colts (2-2) on Oct. 16. Kickoff is scheduled for 1:00pm EDT in Indianapolis.
The Colts are betting favorites in Week 6, with the spread sitting at -2 (-110).
The Jaguars vs. Colts Over/Under is 42 total points for the game.
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Jaguars vs. Colts Prediction for Week 6
Based on recent trends, the winning team model predicts the Colts will win this Week 6 game with 60.5% confidence.
Based on recent against-the-spread trends, the model predicts the Colts will cover the spread this Week 6 with 59.0% confidence.
Both predictions factor in up-to-date player injuries for both the Jaguars and Colts, plus offensive & defensive matchups, recent games and key player performances this season.
Best Jaguars Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for Jaguars players for Week 6, looking at profitable historical betting trends:
- Zay Jones has hit the Receptions Over in 9 of his last 12 games (+6.75 Units / 50% ROI)
- Christian Kirk has hit the Receptions Over in 12 of his last 17 games (+6.70 Units / 33% ROI)
- Christian Kirk has hit the Receiving Yards Over in 12 of his last 18 games (+4.95 Units / 23% ROI)
- Trevor Lawrence has hit the Completions Over in 11 of his last 17 games (+4.20 Units / 22% ROI)
- Trevor Lawrence has hit the TD Passes Under in 12 of his last 17 games (+4.20 Units / 13% ROI)
Best Colts Player Prop Best Bets Today
And here are some top NFL player prop bets for Colts players for Week 6, looking at profitable historical betting trends:
- Matt Ryan has hit the TD Passes Under in 14 of his last 17 games (+9.35 Units / 32% ROI)
- Nyheim Hines has hit the Rushing Yards Under in 11 of his last 13 games (+8.60 Units / 53% ROI)
- Jonathan Taylor has hit the Receiving Yards Under in 12 of his last 17 games (+5.65 Units / 26% ROI)
- Parris Campbell has hit the Receiving Yards Over in 5 of his last 7 games (+2.75 Units / 36% ROI)
- Matt Ryan has hit the Interceptions Over in 10 of his last 17 games (+2.70 Units / 13% ROI)
Jaguars Betting Trends: ATS, Moneyline, Over/Under
- The Jacksonville Jaguars have scored first in 7 of their last 8 games (+8.00 Units / 92% ROI)
- The Jacksonville Jaguars have hit the 3Q Game Total Under in 12 of their last 17 games (+6.65 Units / 36% ROI)
- The Jacksonville Jaguars have hit the 2H Game Total Under in 12 of their last 17 games (+6.45 Units / 34% ROI)
- The Jacksonville Jaguars have hit the 3Q Moneyline in 4 of their last 6 games (+5.30 Units / 78% ROI)
- The Jacksonville Jaguars have hit the 1Q Moneyline in 4 of their last 6 games (+5.10 Units / 70% ROI)
Colts Betting Trends: ATS, Moneyline, Over/Under
- The Indianapolis Colts have hit the Game Total Under in their last 10 games (+10.00 Units / 91% ROI)
- The Indianapolis Colts have hit the Team Total Under in their last 8 games (+8.00 Units / 89% ROI)
- The Indianapolis Colts have hit the 1H Game Total Under in 8 of their last 10 games (+6.90 Units / 62% ROI)
- The Indianapolis Colts have hit the 3Q Game Total Under in 7 of their last 10 games (+5.00 Units / 45% ROI)
- The Indianapolis Colts have hit the 2H Game Total Under in 9 of their last 13 games (+4.75 Units / 34% ROI)
Jaguars Against the Spread (ATS) Record
Against the spread this NFL season, the Jaguars have gone 2-3 (-1.25 Units / -22.94% ROI).
- Jaguars are 2-3 when betting on the Moneyline for -1.5 Units / -20.83% ROI
- Jaguars are 3-2 when betting the Over for +0.75 Units / 13.51% ROI
- Jaguars are 2-3 when betting the Under for -1.3 Units / ROI
Colts Against the Spread (ATS) Record
Against the spread this NFL season, the Colts have gone 2-3 (-1.25 Units / -23.36% ROI).
- Colts are 2-2 when betting on the Moneyline for -0.2 Units / -2.22% ROI
- Colts are 0-5 when betting the Over for -5.5 Units / -100% ROI
- Colts are 5-0 when betting the Under for +5 Units / 90.91% ROI
Jacksonville Jaguars: Keys to the Game vs. the Indianapolis Colts
The Jaguars are winless (0-12) when the opposing team converts 55% or more of its red zone chances into touchdowns since the 2021 season — worst in NFL; League Avg: .436.
The Jaguars are 1-8 (.111) when allowing 5 or more explosive passes since the 2021 season — worst in NFL; League Avg: .428.
The Jaguars are 1-17 (.056) when having a turnover margin within one of the opposing team since the 2020 season — worst in NFL; League Avg: .497.
The Jaguars are 1-16 (.059) when allowing 10 or more rushes of four or more yards since the 2021 season — worst in NFL; League Avg: .416.
Indianapolis Colts: Keys to the Game vs. the Jacksonville Jaguars
The Colts were 5-1 (.833) vs bottom 10 run defenses last season — tied for 7th-best in NFL; League Avg: .635.
The Colts are 5-8-1 (.357) when averaging less than 5 yards per rush since the 2021 season — 10th-worst in NFL; League Avg: .486.