Cardinals vs Seahawks Prediction, Odds & Best Prop Bets – NFL, Week 6
Cardinals vs Seahawks Prediction, Odds & Best Prop Bets – NFL, Week 6

The Arizona Cardinals (2-3) visit Lumen Field to take on the Seattle Seahawks (2-3) on Oct. 16. Kickoff is scheduled for 4:05pm EDT in Seattle.

The Cardinals are betting favorites in Week 6, with the spread sitting at -3 (+100).

The Cardinals vs. Seahawks Over/Under is 51 total points for the game.

Bet now on Seahawks vs Cardinals & all NFL games with BetMGM

Cardinals vs. Seahawks Prediction for Week 6

Based on recent trends, the winning team model predicts the Cardinals will win this Week 6 game with 67.5% confidence.

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread this Week 6 with 60.0% confidence.

Both predictions factor in up-to-date player injuries for both the Cardinals and Seahawks, plus offensive & defensive matchups, recent games and key player performances this season.


Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for Cardinals players for Week 6, looking at profitable historical betting trends:

  • Marquise Brown has hit the Receptions Over in 13 of his last 17 games (+10.10 Units / 55% ROI)
  • Darrel Williams has hit the Receptions Over in 8 of his last 10 games (+7.10 Units / 61% ROI)
  • Zach Ertz has hit the Receptions Over in 11 of his last 16 games (+5.70 Units / 31% ROI)
  • Darrel Williams has hit the Rushing Yards Under in 8 of his last 10 games (+5.40 Units / 41% ROI)
  • Rondale Moore has hit the Receiving Yards Under in 8 of his last 11 games (+4.15 Units / 29% ROI)

Best Seahawks Player Prop Best Bets Today

And here are some top NFL player prop bets for Seahawks players for Week 6, looking at profitable historical betting trends:

  • Rashaad Penny has hit the Receiving Yards Under in his last 6 games (+6.00 Units / 82% ROI)
  • Geno Smith has hit the Pass Attempts Under in 7 of his last 8 games (+5.65 Units / 50% ROI)
  • Geno Smith has hit the Interceptions Under in 6 of his last 8 games (+4.80 Units / 56% ROI)
  • Tyler Lockett has hit the Receptions Under in 10 of his last 15 games (+4.25 Units / 23% ROI)
  • Geno Smith has hit the Completions Over in 6 of his last 8 games (+3.80 Units / 43% ROI)

  • The Arizona Cardinals have hit the 2H Game Total Over in 11 of their last 16 games (+6.40 Units / 36% ROI)
  • The Arizona Cardinals have hit the 4Q Moneyline in their last 5 games (+5.80 Units / 114% ROI)
  • The Arizona Cardinals have hit the 1H Game Total Under in their last 5 away games (+5.00 Units / 94% ROI)
  • The Arizona Cardinals have hit the 1Q Game Total Under in their last 5 away games (+5.00 Units / 88% ROI)
  • The Arizona Cardinals have covered the 4Q Spread in their last 5 games (+5.00 Units / 80% ROI)

  • The Seattle Seahawks have hit the 1H Moneyline in 8 of their last 10 games (+9.50 Units / 62% ROI)
  • The Seattle Seahawks have hit the 1H Game Total Over in 9 of their last 11 games (+7.85 Units / 66% ROI)
  • The Seattle Seahawks have covered the 1H Spread in 8 of their last 9 games (+6.80 Units / 69% ROI)
  • The Seattle Seahawks have covered the 1Q Spread in 12 of their last 17 games (+6.35 Units / 33% ROI)
  • The Seattle Seahawks have hit the 2Q Moneyline in 7 of their last 11 games (+6.15 Units / 43% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals have gone 3-2 (+0.75 Units / 13.51% ROI).

  • Cardinals are 2-3 when betting on the Moneyline for +0 Units / 0% ROI
  • Cardinals are 2-3 when betting the Over for -1.3 Units / -23.64% ROI
  • Cardinals are 3-2 when betting the Under for +0.8 Units / ROI

Seahawks Against the Spread (ATS) Record

Against the spread this NFL season, the Seahawks have gone 2-3 (-1.3 Units / -23.64% ROI).

  • Seahawks are 2-3 when betting on the Moneyline for +0.75 Units / 14.56% ROI
  • Seahawks are 3-2 when betting the Over for +0.75 Units / 13.51% ROI
  • Seahawks are 2-3 when betting the Under for -1.3 Units / -23.85% ROI

Arizona Cardinals: Keys to the Game vs. the Seattle Seahawks

The Cardinals are 11-3 (.786) when possessing the ball longer than their opponent since the 2021 season — eighth-best in NFL. The Seahawks has allowed an average time of possession of 34 min and 14 s since the 2021 season — second-highest in NFL.

The Cardinals are 9-6 (.600) when passing for 250 or more yards since the 2021 season — tied for 10th-best in NFL. The Seahawks have allowed 264.2 passing yards per game since the 2021 season — second-worst in NFL.

The Cardinals are winless (0-3) when the opposing team commits less than 60 yards in penalties this season — tied for worst in NFL; League Avg: .471.

The Cardinals are 11-3 (.786) when possessing the ball longer than their opponent since the 2021 season — 8th-best in NFL; League Avg: .655.

Seattle Seahawks: Keys to the Game vs. the Arizona Cardinals

The Seahawks are 2-8 (.200) when converting less than 55% of its red zone chances into touchdowns since the 2021 season — 2nd-worst in NFL; League Avg: .451.

The Seahawks are 2-8 (.200) when within 7 points at the two minute warning since the 2021 season — tied for 3rd-worst in NFL; League Avg: .493.

  
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