The San Francisco 49ers (3-2) visit Mercedes-Benz Stadium to take on the Atlanta Falcons (2-3) on Oct. 16. Kickoff is scheduled for 1:00pm EDT in Atlanta.
The 49ers are betting favorites in Week 6, with the spread sitting at -5.5 (-110).
The 49ers vs. Falcons Over/Under is 43 total points for the game.
Bet now on Falcons vs 49ers & all NFL games with BetMGM
49ers vs. Falcons Prediction for Week 6
Based on recent trends, the winning team model predicts the 49ers will win this Week 6 game with 64.0% confidence.
Based on recent against-the-spread trends, the model predicts the Falcons will cover the spread this Week 6 with 62.0% confidence.
Both predictions factor in up-to-date player injuries for both the 49ers and Falcons, plus offensive & defensive matchups, recent games and key player performances this season.
Best 49ers Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for 49ers players for Week 6, looking at profitable historical betting trends:
- Jimmy Garoppolo has hit the Completions Under in 13 of his last 16 games (+9.50 Units / 46% ROI)
- Deebo Samuel has hit the Receptions Under in 14 of his last 19 games (+8.00 Units / 30% ROI)
- George Kittle has hit the Receptions Under in 11 of his last 16 games (+4.50 Units / 19% ROI)
- Jimmy Garoppolo has hit the Rushing Yards Under in 8 of his last 11 games (+4.05 Units / 29% ROI)
- Ray-Ray McCloud has hit the Receiving Yards Over in 5 of his last 6 games (+3.80 Units / 55% ROI)
Best Falcons Player Prop Best Bets Today
And here are some top NFL player prop bets for Falcons players for Week 6, looking at profitable historical betting trends:
- Cordarrelle Patterson has hit the Receiving Yards Under in 13 of his last 15 games (+10.25 Units / 53% ROI)
- Anthony Firkser has hit the Receptions Under in his last 8 games (+8.20 Units / 74% ROI)
- Cordarrelle Patterson has hit the Receptions Under in 12 of his last 15 games (+8.15 Units / 38% ROI)
- Kyle Pitts has hit the Receiving Yards Under in 6 of his last 7 games at home (+4.80 Units / 54% ROI)
- Kyle Pitts has hit the Receptions Under in 5 of his last 6 games at home (+4.05 Units / 54% ROI)
49ers Betting Trends: ATS, Moneyline, Over/Under
- The San Francisco 49ers have hit the Game Total Under in 11 of their last 13 games (+8.80 Units / 62% ROI)
- The San Francisco 49ers have covered the Spread in 13 of their last 17 games (+8.75 Units / 47% ROI)
- The San Francisco 49ers have covered the 1H Spread in 13 of their last 17 games (+8.70 Units / 48% ROI)
- The San Francisco 49ers have hit the 1H Moneyline in 13 of their last 17 games (+8.10 Units / 28% ROI)
- The San Francisco 49ers have hit the 1H Game Total Under in 9 of their last 11 games (+7.85 Units / 64% ROI)
Falcons Betting Trends: ATS, Moneyline, Over/Under
- The Atlanta Falcons have covered the 4Q Spread in 8 of their last 10 games (+5.90 Units / 48% ROI)
- The Atlanta Falcons have hit the 2H Moneyline in 5 of their last 6 games (+5.50 Units / 79% ROI)
- The Atlanta Falcons have hit the 4Q Moneyline in 6 of their last 10 games (+5.20 Units / 48% ROI)
- The Atlanta Falcons have hit the 3Q Game Total Under in 6 of their last 7 games at home (+5.00 Units / 66% ROI)
- The Atlanta Falcons have hit the 1H Game Total Over in 8 of their last 11 games (+4.75 Units / 40% ROI)
49ers Against the Spread (ATS) Record
Against the spread this NFL season, the 49ers have gone 3-2 (+0.8 Units / 14.55% ROI).
- 49ers are 3-2 when betting on the Moneyline for -0.85 Units / -7.39% ROI
- 49ers are 1-4 when betting the Over for -3.4 Units / -61.82% ROI
- 49ers are 4-1 when betting the Under for +2.9 Units / ROI
Falcons Against the Spread (ATS) Record
Against the spread this NFL season, the Falcons have gone 5-0 (+5 Units / 90.91% ROI).
- Falcons are 2-3 when betting on the Moneyline for -1 Units / -19.8% ROI
- Falcons are 3-2 when betting the Over for +0.8 Units / 14.55% ROI
- Falcons are 2-3 when betting the Under for -1.3 Units / -23.64% ROI
San Francisco 49ers: Keys to the Game vs. the Atlanta Falcons
The 49ers are 11-6 (.647) when allowing less than 3 sacks since the 2021 season — 10th-best in NFL. The Falcons have averaged just 1.2 sacks per game over that time span — worst in NFL.
The 49ers are undefeated (4-0) when committing less than 60 yards in penalties this season — tied for best in NFL; League Avg: .521.
The 49ers are undefeated (7-0) vs bottom 10 run offenses since the 2021 season — tied for best in NFL; League Avg: .536.
The 49ers are undefeated (10-0) when not throwing an interception since the 2021 season — tied for best in NFL; League Avg: .652.
Atlanta Falcons: Keys to the Game vs. the San Francisco 49ers
The Falcons are winless (0-3) when sacking the QB 3 or more times since the 2021 season — worst in NFL; League Avg: .638.
The Falcons are winless (0-1) when the opposing team commits less than 30 yards in penalties since the 2021 season — tied for worst in NFL; League Avg: .491.