Can Pittsburgh hang tough as a huge underdog in Buffalo? Find out where we lean in our Steelers-Bills picks.
The 1-3 Pittsburgh Steelers haven't been a two-touchdown underdog in more than 50 years, but that could be the case when Kenny Pickett makes his first career start at quarterback against the 3-1 Buffalo Bills. Pittsburgh won in Buffalo last year as a 6.5-point dog and is 19-9-2 ATS in its last 30 when catching points.
Can the Steelers stay within the big number, or will the Bills pull away for a blowout victory?
Here are our Steelers-Bills picks and predictions for NFL Week 5 (odds via Caesars Sportsbook, DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).