NFL Best Bets Week 5: Matchups, Odds, Picks, Predictions
NFL Best Bets Week 5: Matchups, Odds, Picks, Predictions

Entering this week, there is just one winless NFL team and one undefeated team – the Philadelphia Eagles – remaining. We have highlighted the odds, movements, and our NFL best bets for Week 5.

Through the first four weeks of the season, 15 teams have started 2-2, which equals the mark set in 2017 for the most 2-2 teams in a single season in NFL history, per ESPN Stats & Info. Will there continue to be great parity around the league, or will teams start to separate themselves?

Here are our best bets for the NFL's slate in Week 5 (odds via Caesars Sportsbook, FanDuel Sportsbook, DraftKings Sportsbook; pick confidence is based on a 1-to-5-star scale).

Sunday's NFL Schedule and Odds

(odds via DraftKings)

  • New York Giants (+295) vs. Green Bay Packers (-360)
  • Pittsburgh Steelers (+600) vs. Buffalo Bills (-850)
  • Los Angeles Chargers (-130) vs. Cleveland Browns (+110)
  • Chicago Bears (+290) vs. Minnesota Vikings (-350)
  • Detroit Lions (+145) vs. New England Patriots (-170)
  • Seattle Seahawks (+190) vs. New Orleans Saints (-225)
  • Miami Dolphins (-175) vs. New York Jets (+150)
  • Atlanta Falcons (+350) vs. Tampa Bay Buccaneers (-435)
  • Tennessee Titans (-130) vs. Washington Commanders (+110)
  • Houston Texans (+265) vs. Jacksonville Jaguars (-320)
  • San Francisco 49ers (-260) vs. Carolina Panthers (+220)
  • Dallas Cowboys (+190) vs. Los Angeles Rams (-225)
  • Philadelphia Eagles (-215) vs. Arizona Cardinals (+185) 
  • Cincinnati Bengals (+150) vs. Baltimore Ravens (-175)
  • Las Vegas Raiders (+260) vs. Kansas City Chiefs (-315)

Sunday's NFL Best Bets

  • Moneyline: 49ers (-260 via DraftKings) ???
  • Spread: Bills -14 (-110 via Caesars) ????
  • Total: Cowboys-Rams Under 43.5 (-110 via FanDuel) ????
  • Upset: Cardinals (+198 via FanDuel) ???
  • Player Prop: Justin Herbert Over 276.5 passing yards (-115 via DraftKings) ???

Sunday's NFL Top Picks

  
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