Plug your nose and back the Chicago Bears during the Minnesota Vikings' first game back from London. Let's dive in with our Week 5 against the spread picks.
After all but one game in Week 4 featured a point spread of seven points or less, there are five favorites of at least a touchdown in Week 5. Two of those games are on our card for the best against the spread NFL picks, along with a small favorite that may be flying under the radar following a 1-3 start.
Here are our best NFL against the spread bets for Week 5 (o dds via Caesars, FanDuel, and DraftKings sportsbooks).
Week 5 NFL Against the Spread Picks
Top NFL Against the Spread Predictions
Chicago has won during three of its last four visits to Minnesota, and the Bears should be live underdogs once again in Week 5 with a defense that's held three of its first four opponents to 20 points or fewer. Meanwhile, as punchless as Chicago's attack has been overall so far in 2022, the Bears rank third in the NFL with 177 rushing yards per game. They should be able to do some damage against Minnesota's 23rd-ranked run defense.