The Arizona Cardinals (1-3) are on the road in Week 5 to face the San Francisco 49ers (2-2). Kickoff from Levi’s Stadium is at 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Cardinals vs 49ers odds, and'make our expert NFL picks and predictions.
The Cardinals have lost 2 straight and are coming off their worst loss in the last 2 seasons, falling 42-14 at home to the Washington Commanders as 3.5-point favorites.
The Niners completely dominated the New England Patriots in a 30-13 home win, covering the 10.5-points spread as favorites, and sacking the Patriots 6 times.
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