Houston Astros vs Cleveland Guardians Prediction, 9/27/2024 MLB Picks, Best Bets & Odds

The Houston Astros are set to go head to head with the Cleveland Guardians at Progressive Field on Friday, September 27, 2024. That contest is set to start at 7:10 PM EST at Progressive Field in Cleveland, OH. This games report has current odds, betting trends, and free picks against the spread.

  
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