The Buffalo Bills (2-0) are considered 5.5-point favorites heading into their matchup on Monday, September 23, 2024 versus the Jacksonville Jaguars (0-2). For this game, an over/under of 45.5 has been set.
Are you looking to place a parlay bet on this game? See insights, including team to score first, first-half scoring props, and prop bets for the top players, int the article below.
Bills vs. Jaguars game odds
NFL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 7:41 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
- Spread: Bills +5.5 (-110 to cover)
- Moneylines: Bills -250, Jaguars +200
- Total: 45.5 points (Over: -110, Under: -110)
- Pick ATS: Bills (-5.5)
- Pick OU: Under (45.5)
- Prediction:
Bills 28 – Jaguars 14