San Francisco 49ers vs. Los Angeles Rams odds, picks and predictions
San Francisco 49ers vs. Los Angeles Rams odds, picks and predictions

The San Francisco 49ers (1-1) are visiting the Los Angeles Rams (0-2) on Sunday afternoon in a rivalry game between NFC West foes. Kickoff from SoFi Stadium in Inglewood, Calif., is set for 4:25 p.m. ET (FOX).

Let’s analyze BetMGM Sportsbook’s NFL odds around the 49ers vs. Rams odds, and'make our expert NFL picks and predictions.

The 49ers are coming off a shocking 23-17 loss to the Minnesota Vikings in Week 2, a game in which they were 4-point road favorites. RB Christian McCaffrey remains out with Achilles tendinitis, and WR Deebo Samuel will also miss this game with a calf injury.

The Rams are 0-2 for the 1st time under coach Sean McVay, with their most recent loss being a 41-10 defeat at the hands of the Arizona Cardinals. They’re arguably the most injured team in the NFL right now, missing WRs Cooper Kupp and Puka Nacua, starting linemen Jonah Jackson and Steve Avila, as well as S John Johnson III, among others.

  
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