49ers vs. Rams best bets, picks and odds | Week 3
49ers vs. Rams best bets, picks and odds | Week 3

Check out best bets for when NFC West foes meet as the San Francisco 49ers (1-1) and the Los Angeles Rams (0-2) square off on Sunday, September 22, 2024 at SoFi Stadium.

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Best against the spread pick

  • Pick ATS: Rams (+6.5)
  • San Francisco is 1-1-0 against the spread this season.
  • Los Angeles is winless against the spread this season.

Best over/under pick

  • Pick OU: Over (43.5)
  • The teams combine to score 39.5 points per game, 4.0 fewer points than this matchup’s total.
  • These teams give up 54.5 points per game combined, 11.0 more points than this matchup’s over/under.

Best moneyline bet

  • Moneyline: 49ers (-300), Rams (+240)
  • Prediction:
    49ers 25 – Rams 22
  • Based on this game’s moneyline, the 49ers have an implied win probability of 75.0%.
  • San Francisco has been the moneyline favorite just two other times so far this season, and they split the two games.
  • The 49ers have not played a game this season with moneyline odds of -300 or shorter.
  • Los Angeles lost the only game it has played as the underdog this season.
  • The Rams have not entered a game this season as a bigger underdog on the moneyline than the +240 odds on them winning this game.

How to watch 49ers vs. Rams

  • When: Sunday, September 22, 2024 at 4:25 p.m. ET
  • Where: SoFi Stadium in Inglewood, California
  • TV Info: FOX
  • Live stream: Watch on Fubo!

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