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NFL Week 3 is when teams start to head in separate directions. Well, unless they're the Carolina Panthers, who've already firmly established their direction for the season ahead.
The first two weeks are for testing the waters. We, as bettors, are able to get a better sense of our offseason expectations and either be pleasantly surprised or rightfully disappointed.
Now, it's time for those with any true Super Bowl odds hopes to either right the ship or put the hammer down.
Of course, injuries now also take their toll and the affect of several big-name stars landing on the shelf was already seen in the NFL Week 3 odds from our best NFL betting sites.
Mike Spector set the table with his Patriots vs. Jets early picks, and the rest of our NFL Week 3 predictions can be found below, along with the NFL odds for each matchup.
NFL picks & predictions Week 3
Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!
- Patriots vs. Jets early picks
- Patriots vs. Jets prediction
- Patriots vs. Jets player props
- Patriots vs. Jets parlay
- Aaron Rodgers player props
- Breece Hall player props
- First touchdown scorer predictions for TNF
- Bears vs. Colts player props
- Texans vs. Vikings player props
- Jets vs. Titans player props
- Eagles vs. Saints player props
- Ravens vs. Cowboys prediction
- Ravens vs. Cowboys player props
- 49ers vs. Rams prediction
- 49ers vs. Rams player props
- Lions vs. Cardinals player props
- Chiefs vs. Falcons early picks
- Chiefs vs. Falcons prediction
- Chiefs vs. Falcons SNF player props
- Chiefs vs. Falcons pa rlay
- Patrick Mahomes player props
- Travis Kelce player props
- First touchdown scorer predictions for SNF
- Jaguars vs. Bills early picks
- Jaguars vs. Bills prediction
- Jaguars vs. Bills player props
- Commanders vs. Bengals early picks
- Commanders vs. Bengals prediction
- Commanders vs. Bengals player props
Don't miss the rest of our Week 3 NFL picks. Listed odds for all games via bet365 unless stated otherwise.
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NFL odds for Thursday
- When: Thursday, Sept. 19 – 8:15 p.m. ET
- Where: MetLife Stadium, East Rutherford, N.J.
- How to watch: Prime Video
- Moneyline: Patriots +230 | Jets -280
- Spread: Patriots +6 (-110) | Jets -6 (-110)
- Total: 37.5 (-110/-110)
NFL odds for Sunday
- When: Sunday, Sept. 22 – 1 p.m. ET
- Where: Huntington Bank Field, Cleveland
- How to watch: FOX
- Moneyline: Giants +235 | Browns -290
- Spread: Giants +6.5 (-115) | Browns -6.5 (-105)
- Total: 38.5 (-110/-110)
- When: Sunday, Sept. 22 – 1 p.m. ET
- Where: Nissan Stadium, Nashville
- How to watch: FOX
- Moneyline: Packers +130 | Titans -155
- Spread: Packers +3 (-120) | Titans -35 (+100)
- Total: 36.5 (-110/-110)
- When: Sunday, Sept. 22 – 1 p.m. ET
- Where: Lucas Oil Stadium, Indianapolis
- How to watch: CBS
- Moneyline: Bears +105 | Colts -125
- Spread: Bears +1.5 (-110) | Colts -1.5 (-110)
- Total: 42.5 (-110/-110)
- When: Sunday, Sept. 22 – 1 p.m. ET
- Where: U.S. Bank Stadium, Minneapolis
- How to watch: CBS
- Moneyline: Texans -140 | Vikings +120
- Spread: Texans -2.5 (-110) | Vikings +2.5 (-110)
- Total: 45 (-110/-110)
- When: Sunday, Sept. 22 – 1 p.m. ET
- Where: Caesars Superdome, New Orleans
- How to watch: FOX
- Moneyline: Eagles -115 | Saints -105
- Spread: Eagles -1 (-110) | Saints +1 (-110)
- Total: 49.5 (-110/-110)
- When: Sunday, Sept. 22 – 1 p.m. ET
- Where: Acrisure Stadium, Pittsburgh
- How to watch: CBS
- Moneyline: Chargers +110 | Steelers -130
- Spread: Chargers +2 (-110) | Steelers -2 (-110)
- Total: 36 (-110/-110)
- When: Sunday, Sept. 22 – 1 p.m. ET
- Where: Raymond James Stadium, Tampa, Fla.
- How to watch: FOX
- Moneyline: Broncos +245 | Buccaneers -305
- Spread: Broncos +6.5 (-105) | Buccaneers -6.5 (-115)
- Total: 39.5 (-110/-110)
- When: Sunday, Sept. 22 – 4:05 p.m. ET
- Where: Allegiant Stadium, Las Vegas
- How to watch: CBS
- Moneyline: Panthers +205 | Raiders -250
- Spread: Panthers +5.5 (-110) | Raiders -5.5 (-110)
- Total: 40.5 (-110/-110)
- When: Sunday, Sept. 22 – 4:05 p.m. ET
- Where: Lumen Field, Seattle
- How to watch: CBS
- Moneyline: Dolphins +205 | Seahawks -2 50
- Spread: Dolphins +5.5 (-110) | Seahawks -5.5 (-110)
- Total: 41 (-110/-110)
- When: Sunday, Sept. 22 – 4:25 p.m. ET
- Where: AT&T Stadium, Arlington, Texas
- How to watch: FOX
- Moneyline: Ravens -115 | Cowboys -105
- Spread: Ravens -1 (-110) | Cowboys +1 (-110)
- Total: 48.5 (-110/-110)
- When: Sunday, Sept. 22 – 4:25 p.m. ET
- Where: SoFi Stadium, Inglewood, Calif.
- How to watch: FOX
- Moneyline: 49ers -380 | Rams +300
- Spread: 49ers -8 (-110) | Rams +8 (-110)
- Total: 45.5 (-110/-110)
- When: Sunday, Sept. 22 – 4:25 p.m. ET
- Where: State Farm Stadium, Glendale, Ariz.
- How to watch: FOX
- Moneyline: Lions -155 | Cardinals +130
- Spread: Lions -3 (-105) | Cardinals +3 (-115)
- Total: 51. 5 (-110/-110)
- When: Sunday, Sept. 22 – 8:20 p.m. ET
- Where: Mercedes-Benz Stadium, Atlanta
- How to watch: NBC/Peacock
- Moneyline: Chiefs -220 | Falcons +180
- Spread: Chiefs -4.5 (-110) | Falcons +4.5 (-110)
- Total: 46.5 (-110/-110)
- When: Monday, Sept. 23 – 7:30 p.m. ET
- Where: Highmark Stadium, Orchard Park, N.Y.
- How to watch: ESPN
- Moneyline: Jaguars +210 | Bills -260
- Spread: Jaguars +5.5 (-110) | Bills -5.5 (-110)
- Total: 46 (-110/-110)
- When: Monday, Sept. 23 – 8:15 p.m. ET
- Where: Paycor Stadium, Cincinnati
- How to watch: ABC
- Moneyline: Commanders +310 | Bengals -390
- Spread: Commanders +8 (-110) | Bengals -8 (-110)
- Total: 48 (-110/-110)
- NFL survivor picks
- NFL ATS picks Week 3
- NFL upset picks
- Anytime TD scorer predictions
- NFL best bets Week 3
- NFL parlay picks Week 3
- NFL player props Week 3
- NFC South odds
- Marvin Harrison Jr. Rookie of the Year odds
- Comparing your team's Super Bowl odds against Harvard acceptance rate
- NFL power rankings & Super Bowl odds
- NFL rookie QBs and their 2024 OROY odds
- NFL awards odds
- NFL division winners
- 5 under-25 QBs with best NFL MVP odds
- Which of the 5 highest paid NFL players are getting the best MVP odds?
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NFL odds for Monday
NFL picks roundup: Week 3
NFL feature picks
NFL betting odds pages
| Super Bowl Odds | NFL MVP Odds | NFL Offensive Player of the Year Odds |
| NFL Defensive Player of the Year Odds | NFL Offensive Rookie of the Year Odds | NFL Defensive Rookie of the Year Odds |
| NFL Coach of the Year Odds | NFL Comeback Player of the Year Odds | NFL Win Totals Odds |
| NFL Playoff Odds | NFL Draft Odds |
Here are our best NFL betting sites:
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