First look: Jacksonville Jaguars at Buffalo Bills odds and lines
First look: Jacksonville Jaguars at Buffalo Bills odds and lines

The Jacksonville Jaguars (0-2) travel to meet the Buffalo Bills (2-0) at Highmark Stadium in Week 3 in the first of 2 NFL games Monday night. Kickoff is scheduled for 7:30 p.m. ET (ESPN). Below, we look at Jaguars vs. Bills odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week. The Cincinnati Bengals host the Washington Commanders in the 2nd game of the night at 8:15 p.m. ET (ABC).

The Jaguars head into Buffalo looking for their 1st victory of the season after a pair of one-score losses. Jacksonville blew a Week 1 lead in Miami, falling 20-17, although it did cover as a 3.5-point underdog with the Under (49) cashing.

In the home opener in Week 2, the Jaguars lost as 3-point favorites to the Cleveland Browns 18-13. Jacksonville fell behind 16-3 before making a valiant comeback. The Jags closed the gap to 16-13, but a late safety sealed the win for Cleveland as the Under (41.5) cashed, again.

For the Bills, they were pushed hard in Week 1 by the Arizona Cardinals, eventually holding off the visitors 34-28, although Buffalo failed to cover as a 7-point favorite as the Over (45) cashed.

  
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