Rams vs Cardinals Prediction, Odds & Best Prop Bets: NFL, Week 2
Rams vs Cardinals Prediction, Odds & Best Prop Bets: NFL, Week 2

The Los Angeles Rams (0-1-0) visit State Farm Stadium to take on the Arizona Cardinals (0-1-0) on Sep. 15. Kickoff is scheduled for 4:05pm EDT in Glendale, AZ.

The Cardinals are betting favorites in this matchup, with the spread sitting at -1.5 (-110).

The Rams vs. Cardinals Over/Under is 49.5 total points for the game.

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Rams vs. Cardinals Prediction

The winning team model predicts the Rams will win this game with 51.5% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Based on recent against-the-spread trends, the model predicts the Rams will cover the spread with 51.5% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Rams players this playoff game, looking at profitable historical betting trends:

Best Rams Player Prop Bets Today

  • Colby Parkinson has hit the Receiving Yards Over in 9 of his last 11 games (+6.50 Units / 50% ROI)
  • Colby Parkinson has hit the Receptions Over in 6 of his last 7 games (+6.05 Units / 69% ROI)
  • Jimmy Garoppolo has hit the Interceptions Over in his last 6 games (+6.00 Units / 69% ROI)
  • Kyren Williams has hit the Carries Over in 9 of his last 12 games (+6.00 Units / 46% ROI)
  • Kyren Williams has hit the Rushing Yards Over in 9 of his last 12 games (+5.65 Units / 41% ROI)

And here are some top NFL player prop bets for Cardinals players for this matchup, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today

  • James Conner has hit the Longest Reception Under in 7 of his last 8 games (+5.75 Units / 58% ROI)
  • Desmond Ridder has hit the Rushing Yards Over in his last 5 games at home (+5.00 Units / 86% ROI)
  • James Conner has hit the Longest Rush Over in his last 5 games (+5.00 Units / 85% ROI)
  • Chris Moore has hit the Receiving Yards Over in 6 of his last 7 games (+4.85 Units / 58% ROI)
  • James Conner has hit the Receiving Yards Under in 10 of his last 14 games (+4.85 Units / 26% ROI)

  • The Los Angeles Rams have covered the 1Q Spread in 14 of their last 21 games (+7.00 Units / 28% ROI)
  • The Los Angeles Rams have hit the Team Total Over in 7 of their last 8 games (+5.90 Units / 58% ROI)
  • The Los Angeles Rams have hit the Moneyline in 12 of their last 21 games (+5.80 Units / 19% ROI)
  • The Los Angeles Rams have covered the Spread in 12 of their last 21 games (+4.30 Units / 19% ROI)
  • The Los Angeles Rams have hit the 3Q Moneyline in 7 of their last 13 games (+4.25 Units / 24% ROI)

  • The Arizona Cardinals have hit the 2Q Game Total Over in 13 of their last 18 games (+7.85 Units / 38% ROI)
  • The Arizona Cardinals have hit the 2H Moneyline in 6 of their last 8 games (+7.10 Units / 89% ROI)
  • The Arizona Cardinals have hit the Game Total Over in 7 of their last 9 games at home (+4.80 Units / 48% ROI)
  • The Arizona Cardinals have scored last in 5 of their last 7 games at home (+4.35 Units / 60% ROI)
  • The Arizona Cardinals have hit the Team Total Over in 6 of their last 8 games at home (+3.95 Units / 40% ROI)

Rams Against the Spread (ATS) Record

Against the spread this NFL preseason, the Rams went 0-1 (-1.1 Units / -100% ROI).

  • Rams are 0-1 when betting on the Moneyline for -1 Units / -100% ROI
  • Rams are 0-1 when betting the Over for -1.15 Units / -100% ROI
  • Rams are 1-0 when betting the Under for +1 Units / ROI

Cardinals Against the Spread (ATS) Record

Against the spread this NFL preseason, the Cardinals went 1-0 (+1 Units / 90.91% ROI).

  • Cardinals are 0-1 when betting on the Moneyline for -1 Units / -100% ROI
  • Cardinals are 1-0 when betting the Over for +1 Units / 90.91% ROI
  • Cardinals are 0-1 when betting the Under for -1.1 Units / -100% ROI

Los Angeles Rams: Keys to the Game vs. the Arizona Cardinals

The Rams were 1-4 (.200) vs top 10 offenses last season — T-7th-worst in NFL; League Avg: .359.

The Rams were 3-1 (.750) when forcing at least one fumble last season — 8th-best in NFL; League Avg: .618.

The Rams were 3-2 (.600) when sacking the QB 3 or more times last season — T-10th-worst in NFL; League Avg: .650.

The Rams were 5-2 (.714) at home last season — 7th-best in NFL; League Avg: .558.

Arizona Cardinals: Keys to the Game vs. the Los Angeles Rams

The Cardinals were winless (0-3) when forcing 2 or more turnovers last season — worst in NFL; League Avg: .707.

The Cardinals were winless (0-10) when scoring less than 22 points last season — T-worst in NFL; League Avg: .254.

The Cardinals are winless (0-13) when losing at least one fumble since the 2022 season — worst in NFL; League Avg: .384.

The Cardinals were 1-6 (.143) when sacking the QB 3 or more times last season — 2nd-worst in NFL; League Avg: .650.

Additional Matchup Notes for Los Angeles Rams vs. Arizona Cardinals

The Cardinals ran successful plays on 46.6% of rush attempts with motion last season — 4th-best in NFL. The Rams allowed successful plays on 46.9% of rush attempts against motion last season — 3rd-worst in NFL.

  
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