NFL Predictions Week 1 2024: Picks & Odds for Marquee Games

It's time.

The 2024-25 NFL season kicks off Thursday at 8:20 p.m. ET with a special edition of the Sunday Night Football odds when the Baltimore Ravens visit the Kansas City Chiefs in an AFC Championship Game rematch.

The Chiefs – the reigning Super Bowl champions – are again the favorites by the 2025 Super Bowl odds. Chiefs Patrick Mahomes and Ravens counterpart Lamar Jackson also front several of the main NFL awards odds.

The Ravens vs. Chiefs odds from our best NFL betting sites list the hosts as short favorites. The Philadelphia Eagles will then be favorites in Brazil on Friday against the Green Bay Packers, according to the Packers vs. Eagles odds.'

Action continues with a full Sunday slate before Week 1 concludes with the Monday Night Football odds as the San Francisco 49ers host the New York Jets.

NFL picks & predictions Week 1

• Ravens vs. Chiefs odds
• Ravens vs. Chiefs prediction (coming soon)
• Ravens vs. Chiefs player props (coming soon)
• Ravens vs. Chiefs parlay (coming soon)
• Lamar Jackson vs. Patrick Mahomes player props (coming soon)
• Travis Kelce player props (coming soon)
• Packers vs. Eagles odds
• Packers vs. Eagles prediction (coming soon)
• Packers vs. Eagles player props (coming soon)
• Packers vs. Eagles parlay (coming soon)
• Jordan Love vs. Jalen Hurts player props (coming soon)
• Cardinals vs. Bills player props (coming soon)
• Titans vs. Bears prediction (coming soon)
• Caleb Williams player props (coming soon)
• Patriots vs. Bengals player props (coming soon)
• Texans vs. Colts player props (coming soon)
• Cowboys vs. Browns prediction (coming soon)
• Cowboys vs. Browns player props (coming soon)
• Ce eDee Lamb player props (coming soon)
• Jayden Daniels player props (coming soon)
• Rams vs. Lions odds (coming soon)
• Rams vs. Lions prediction (coming soon)
• Rams vs. Lions player props (coming soon)
• Rams vs. Lions parlay (coming soon)
• Matthew Stafford vs. Jared Goff player props (coming soon)
• Amon-Ra St. Brown player props (coming soon)
• Jets vs. 49ers odds (coming soon)
• Jets vs. 49ers prediction (coming soon)
• Jets vs, 49ers player props (coming soon)

Don't miss the rest of our Week 1 NFL picks.

NFL odds for Thursday

NFL odds via bet365 and subject to change. Follow the latest NFL scores for line history and matchup info.

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• When: Thursday, Sept. 5 – 8:20 p.m. ET
• Where: GEHA Field at Arrowhead Stadium, Kansas City
• How to watch: NBC, Peacock
• Moneyline: Ravens (+125) | Chiefs (-150)
• Spread: Ravens +3 (-120) | Chiefs -3 (+100)
• Total: 46 (-110/-110)

NFL odds for Friday

• When: Friday, Sept. 6 – 8:15 p.m. ET
• Where: Corinthians Arena, Sao Paulo, Brazil
• How to watch: Peacock
• Moneyline: Packers (+125) | Eagles (-150)
• Spread: Packers +2.5 (+100) | Eagles -2.5 (-120)
• Total: 48.5 (-110/-110)

NFL odds for Sunday

• When: Sunday, Sept. 8 – 1 p.m. ET
• Where: Highmark Stadium, Orchard Park, NY
• How to watch: CBS
• Moneyline: Cardinals (+220) | Bills (-270)
• Spread: Cardinals +6 (-110) | Bills -6 (-110)
• < b>Total: 48 (-110/-110)

• When: Sunday, Sept. 8 – 1 p.m. ET
• Where: Lucas Oil Stadium, Indianapolis
• How to watch: CBS
• Moneyline: Texans (-140) | Colts (+120)
• Spread: Texans -2.5 (-110) | Colts +2.5 (-110)
• Total: 49 (-110/-110)

• When: Sunday, Sept. 8 – 1 p.m. ET
• Where: Paycor Stadium, Cincinnati
• How to watch: CBS
• Moneyline: Patriots (+325) | Bengals (-425)
• Spread: Patriots +8.5 (-105) | Bengals -8.5 (-115)
• Total: 40.5 (-110/-110)

• When: Sunday, Sept. 8 – 1 p.m. ET
• Where: Soldier Field, Chicago
• How to watch: FOX
• Moneyline: Titans (+170) | Bears -205)
• Spread: Titans +4.5 (-110) | Bears -4.5 (-110)
• Total: 45.5 (-110/-110)

• When: Sunday, Sept. 8 – 4:25 p.m. ET
• Whe re: Cleveland Browns Stadium, Cleveland
• How to watch: FOX
• Moneyline: Cowboys (+125) | Browns (-150)
• Spread: Cowboys +2.5 (-105) | Browns -2.5 (-115)
• Total: 42 (-110/-110)

• When: Sunday, Sept. 8 – 8:20 p.m. ET
• Where: Ford Field, Detroit
• How to watch: NBC, Peacock
• Moneyline: Rams (+150) | Lions (-180)
• Spread: Rams +3.5 (-115) | Lions -3.5 (-105)
• Total: 51 (-110/-110)

NFL odds for Monday

• When: Monday, Sept. 9 – 8:20 p.m. ET
• Where: Levi's Stadium, Santa Clara, Calif.
• How to watch: ESPN, ABC
• Moneyline: Jets (+165) | 49ers (-200)
• Spread: Jets +3.5 (-105) | 49ers -3.5 (-115)
• Total: 43.5 (-110/-110)

NFL picks roundup: Week 1

• NFL survivor picks (coming soon)
• NFL upset picks (coming soon)
• NFL ATS picks Week 1 (coming soon)
• Anytime TD scorer predictions (coming soon)
• NFL player props Week 1 (coming soon)
• NFL best bets Week 1 (coming soon)
• NFL parlay picks Week 1 (coming soon)

NFL feature picks

• Comparing your team's Super Bowl odds against Harvard acceptance rate
• NFL power rankings & Super Bowl odds
• NFL rookie QBs and their 2024 OROY odds
• NFL awards odds
• NFL division winners
• 5 under-25 QBs with best NFL MVP odds
• Which of the 5 highest paid NFL players are getting the best MVP odds?

NFL betting odds pages

Here are our best NFL betting sites:

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• bet365 Bonus Code: SBRBONUS | Read our bet365 Review
• FanDuel Promo Code | Read our FanDuel Review
• DraftKings Promo Code | Read our DraftKings Review

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Related pages

• Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)

  
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