The fifth-ranked Clemson Tigers (3-0) look to continue their dominance over No. 21 Wake Forest (3-0) when they meet in a key Atlantic Coast Conference Atlantic Division matchup on Saturday. The Demon Deacons won the division with a 7-1 mark and finished 2021 with a 11-3 overall record. Clemson was second in the division at 6-2 and was 10-3 overall. The Tigers lead the all-time series 69-17-1, including a 26-10-1 record at Wake Forest.
Kickoff from Truist Field in Winston-Sa lem, N.C., is set for noon ET. The Tigers are seven-point favorites in the latest Clemson vs. Wake Forest odds from Caesars Sportsbook, while the over/under for total points scored is 56. (See up-to-date'odds for every game this week on our college football odds page.)'
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