The Cleveland Guardians (19-10) and Houston Astros (10-19) play the middle contest of a 3-game series Wednesday at Minute Maid Park. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Astros odds and make our expert MLB picks and predictions for the best bets.
Season series: Astros lead 1-0
The Guardians lost a wild 10-9 game in 10 innings in the series opener. Cleveland took a 3-0 lead in the top of the 1st inning, but it fell behind 8-3 after 4 frames. The Guardians rallied for 5 runs to tie things up in the top of the 6th, and it led 9-8 after the top of the 10th. But the Astros walked it off on a Victor Caratini 2-run HR off of LHP Hunter Gaddis.
The Astros have pieced together a season-high 3-game winning streak, but remain in last place in the AL West Division. Houston has averaged 10.0 runs per game in the past 3 outings, aided by 2 games played at high elevation in Mexico City over the weekend.