First look: Tennessee Titans at Buffalo Bills odds and lines
First look: Tennessee Titans at Buffalo Bills odds and lines

The Tennessee Titans (0-1) and Buffalo Bills (1-0) head into Week 2 trending in opposite directions after the season opener. They’ll square off next Monday night, the first part of a doubleheader. Kickoff will be at 7:15 p.m. ET (ESPN) from Highmark Stadium in Buffalo. Below, we look at Titans vs. Bills odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Titans were stunned by the New York Giants 21-20 at home Sunday. The Giants scored a touchdown with 1:06 left in the game and successfully converted a 2-point conversion to take a 1-point lead. Tennessee was favored by 5.5 points in that game, failing to even win outright against a Giants team that won 4 games last year.

The Bills stomped the defending champions, beating the Los Angeles Rams 31-10 in the season opener on Thursday night. After being tied 10-10 at halftime, the Bills scored 21 unanswered points in the final 30 minutes, sacking QB Matthew Stafford 7 times and picking him off 3 times. Aside from a couple of INTs, QB Josh Allen looked like an MVP favorite.

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Titans at Bills odds

  
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