2022 NFL Chiefs vs. Chargers lines, picks: Proven model reveals picks for Thursday Night Football matchup
2022 NFL Chiefs vs. Chargers lines, picks: Proven model reveals picks for Thursday Night Football matchup

Two of the most productive young quarterbacks in the league continue their growing rivalry when Justin Herbert and the Los Angeles Chargers kick off Week 2 of the 2022 NFL season by visiting Patrick Mahomes and the AFC West-rival Kansas City Chiefs on Thursday Night Football. Herbert, who is 2-2 with 10 touchdown passes and two interceptions against the Chiefs, led Los Angeles to a 24-19 victory over Las Vegas on Sunday. Kansas City rolled past Arizona 44-21 as Mahomes, who has won two of his three head-to-head matchups vers us Herbert, made five scoring tosses.

Kickoff from Arrowhead Stadium in Kansas City is set for 8:15 p.m. ET. Kansas City is a 3.5-point favorite in the latest Chiefs vs. Chargers odds from Caesars Sportsbook, while the over/under for total points scored is 54.

Before making any Chargers vs. Chiefs picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,500 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2022 NFL season on an incredible 139-98 run on top-rated NFL picks that dates back to the 2017 season.

  
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